Preferential X Chromosome Inactivation as a Mechanism to Explain Female Preponderance in Myasthenia Gravis

Myasthenia gravis (MG) is a neuromuscular autoimmune disease characterized by prevalence in young women (3:1). Several mechanisms proposed as explanations for gender bias, including skewed X chromosome inactivation (XCI) and dosage or sex hormones, are often involved in the development of autoimmuni...

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Main Authors: Vanessa Nicolì, Silvia Maria Tabano, Patrizia Colapietro, Michelangelo Maestri, Roberta Ricciardi, Andrea Stoccoro, Laura Fontana, Melania Guida, Monica Miozzo, Fabio Coppedè, Lucia Migliore
格式: Artigo
語言:Inglês
出版: MDPI AG 2022-04-01
叢編:Genes
主題:
myasthenia gravis
X chromosome inactivation
skewed XCI
gender bias
gender medicines
autoimmune disease
在線閱讀:https://www.mdpi.com/2073-4425/13/4/696
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