Preferential X Chromosome Inactivation as a Mechanism to Explain Female Preponderance in Myasthenia Gravis

Myasthenia gravis (MG) is a neuromuscular autoimmune disease characterized by prevalence in young women (3:1). Several mechanisms proposed as explanations for gender bias, including skewed X chromosome inactivation (XCI) and dosage or sex hormones, are often involved in the development of autoimmuni...

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Detalhes bibliográficos
Main Authors: Vanessa Nicolì, Silvia Maria Tabano, Patrizia Colapietro, Michelangelo Maestri, Roberta Ricciardi, Andrea Stoccoro, Laura Fontana, Melania Guida, Monica Miozzo, Fabio Coppedè, Lucia Migliore
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:Genes
Assuntos:
myasthenia gravis
X chromosome inactivation
skewed XCI
gender bias
gender medicines
autoimmune disease
Acesso em linha:https://www.mdpi.com/2073-4425/13/4/696
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