USP13 functions as a tumor suppressor by blocking the NF-kB-mediated PTEN downregulation in human bladder cancer

Abstract Background USP13 has been reported to be involved in the tumorigenesis of human cancers, however, its functional role and regulatory mechanisms in bladder cancer (BC) remain unclear. Methods q-RT-PCR was performed to examine the expression of miR-130b-3p, miR-301b-3p and USP13 in BC tissue...

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Bibliografiske detaljer
Main Authors: Xiaojun Man, Chiyuan Piao, Xuyong Lin, Chuize Kong, Xiaolu Cui, Yuanjun Jiang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-06-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
USP13
PTEN
NF-kB
Bladder cancer
Online adgang:http://link.springer.com/article/10.1186/s13046-019-1262-4
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