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Anti-Epileptic Effects of FABP3 Ligand MF1 through the Benzodiazepine Recognition Site of the GABA<sub>A</sub> Receptor

Recently, we developed the fatty acid-binding protein 3 (FABP3) ligand MF1 (4-(2-(1-(2-chlorophenyl)-5-phenyl-1H-pyrazol-3-yl)phenoxy) butanoic acid) as a therapeutic candidate for α-synucleinopathies. MF1 shows affinity towards γ-aminobutyric acid type-A (GABA<sub>A</sub>) receptor, but...

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Main Authors: Yasushi Yabuki, Jiaqi Liu, Ichiro Kawahata, Hisanao Izumi, Yasuharu Shinoda, Kohei Koga, Shinya Ueno, Norifumi Shioda, Kohji Fukunaga
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
Colecção:International Journal of Molecular Sciences
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Acesso em linha:https://www.mdpi.com/1422-0067/21/15/5525
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