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The Interplay between CD27dull and CD27bright B Cells Ensures the Flexibility, Stability, and Resilience of Human B Cell Memory
Summary: Memory B cells (MBCs) epitomize the adaptation of the immune system to the environment. We identify two MBC subsets in peripheral blood, CD27dull and CD27bright MBCs, whose frequency changes with age. Heavy chain variable region (VH) usage, somatic mutation frequency replacement-to-silent r...
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Autori principali: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Elsevier
2020-03-01
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Serie: | Cell Reports |
Accesso online: | http://www.sciencedirect.com/science/article/pii/S2211124720301765 |
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