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Pharmacological Inhibition of Gal-3 in Mesenchymal Stem Cells Enhances Their Capacity to Promote Alternative Activation of Macrophages in Dextran Sulphate Sodium-Induced Colitis

Transplantation of mesenchymal stem cells (MSCs) reduces the severity of dextran sulphate sodium- (DSS-) induced colitis. MSCs are able to secrete Galectin-3 (Gal-3), a protein known to affect proliferation, adhesion, and migration of immune cells. We investigate whether newly synthetized inhibitor...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bojana Simovic Markovic, Aleksandar Nikolic, Marina Gazdic, Jasmin Nurkovic, Irena Djordjevic, Nebojsa Arsenijevic, Miodrag Stojkovic, Miodrag L. Lukic, Vladislav Volarevic
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi Limited 2016-01-01
Cyfres:Stem Cells International
Mynediad Ar-lein:http://dx.doi.org/10.1155/2016/2640746
Tagiau: Ychwanegu Tag
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