GATA2 Deficiency in Adult Life Is Characterized by Phenotypic Diversity and Delayed Diagnosis

The transcription factor GATA2 plays a key role in the survival and self-renewal of hematopoietic stem and progenitor cells. Autosomal dominant variants in GATA2 cause a broad spectrum of heterogeneous phenotypes. Here, we present our experience with GATA2 deficiency in a retrospective multicenter a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Oded Shamriz, Naseem Zahalka, Amos J. Simon, Atar Lev, Ortal Barel, Nofar Mor, Yuval Tal, Michael J. Segel, Raz Somech, Hagith Yonath, Ori Toker
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2022-05-01
Edice:Frontiers in Immunology
Témata:
GATA2
exome
primary immune deficiency (PID)
hematopoietic
diagnosis
On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.886117/full
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky