Reduced Function and Diversity of T Cell Repertoire and Distinct Clinical Course in Patients With IL7RA Mutation

The alpha subunit of IL-7 receptor (IL7R7α) is critical for the differentiation of T cells, specifically for the development and maintenance of γδT cells. Mutations in IL7RA are associated with Severe Combined Immunodeficiency (SCID). Infants with IL7RA deficiency can be identified through newborn s...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Front Immunol
Главные авторы: Lev, Atar, Simon, Amos J., Barel, Ortal, Eyal, Eran, Glick-Saar, Efrat, Nayshool, Omri, Birk, Ohad, Stauber, Tali, Hochberg, Amit, Broides, Arnon, Almashanu, Shlomo, Hendel, Ayal, Lee, Yu Nee, Somech, Raz
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650764/
https://ncbi.nlm.nih.gov/pubmed/31379863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01672
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы