Control of Angiogenesis via a VHL/miR-212/132 Axis

A common feature of tumorigenesis is the upregulation of angiogenesis pathways in order to supply nutrients via the blood for the growing tumor. Understanding how cells promote angiogenesis and how to control these processes pharmaceutically are of great clinical interest. Clear cell renal cell carc...

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Autori principali: Zhiyong Lei, Timothy D. Klasson, Maarten M. Brandt, Glenn van de Hoek, Ive Logister, Caroline Cheng, Pieter A. Doevendans, Joost P. G. Sluijter, Rachel H. Giles
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2020-04-01
Serie:Cells
Soggetti:
VHL loss of function
microRNA-212/132
angiogenesis
Accesso online:https://www.mdpi.com/2073-4409/9/4/1017
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