Control of Angiogenesis via a VHL/miR-212/132 Axis

A common feature of tumorigenesis is the upregulation of angiogenesis pathways in order to supply nutrients via the blood for the growing tumor. Understanding how cells promote angiogenesis and how to control these processes pharmaceutically are of great clinical interest. Clear cell renal cell carc...

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Bibliographic Details
Main Authors: Zhiyong Lei, Timothy D. Klasson, Maarten M. Brandt, Glenn van de Hoek, Ive Logister, Caroline Cheng, Pieter A. Doevendans, Joost P. G. Sluijter, Rachel H. Giles
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
VHL loss of function
microRNA-212/132
angiogenesis
Online Access:https://www.mdpi.com/2073-4409/9/4/1017
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