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Feasibility of controlling CD38-CAR T cell activity with a Tet-on inducible CAR design.
Recent clinical advances with chimeric antigen receptor (CAR) T cells have led to the accelerated clinical approval of CD19-CARs to treat acute lymphoblastic leukemia. The CAR T cell therapy is nevertheless associated with toxicities, especially if the CARs are not entirely tumor-specific. Therefore...
Tallennettuna:
Päätekijät: | , , , , , , |
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Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Public Library of Science (PLoS)
2018-01-01
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Sarja: | PLoS ONE |
Linkit: | http://europepmc.org/articles/PMC5976165?pdf=render |
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