Repeated Long-Term Sub-concussion Impacts Induce Motor Dysfunction in Rats: A Potential Rodent Model

Whilst detrimental effects of repeated sub-concussive impacts on neurophysiological and behavioral function are increasingly reported, the underlying mechanisms are largely unknown. Here, we report that repeated sub-concussion with a light weight drop (25 g) in wild-type PVG rats for 2 weeks does no...

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Detalhes bibliográficos
Main Authors: Andrew P. Lavender, Samuel Rawlings, Andrew Warnock, Terry McGonigle, Bailey Hiles-Murison, Michael Nesbit, Virginie Lam, Mark J. Hackett, Melinda Fitzgerald, Ryusuke Takechi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-05-01
Colecção:Frontiers in Neurology
Assuntos:
beamwalk
mild traumatic brain injury
neuromotor function
rotarod
sub-concussion
Acesso em linha:https://www.frontiersin.org/article/10.3389/fneur.2020.00491/full
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