IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases

Inositol-requiring transmembrane kinase/endoribonuclease 1α (IRE1α) is the most prominent and evolutionarily conserved endoplasmic reticulum (ER) membrane protein. This transduces the signal of misfolded protein accumulation in the ER, named as ER stress, to the nucleus as “unfolded protein response...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Raghu Patil Junjappa, Prakash Patil, Kashi Raj Bhattarai, Hyung-Ryong Kim, Han-Jung Chae
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018-06-01
Edice:Frontiers in Immunology
Témata:
autoimmune diseases
cytokines
inflammation
IRE1α
regulated IRE1α-dependent decay
unfolded protein response signaling pathways
On-line přístup:https://www.frontiersin.org/article/10.3389/fimmu.2018.01289/full
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky