Impact of mono- and di-β-galactose moieties in in vitro / in vivo anticancer efficacy of pyropheophorbide-carbohydrate conjugates by photodynamic therapy

To investigate the impact of mono- and di-β-galactose moieties in tumor uptake and photodynamic therapy (PDT) efficacy, HPPH [3-(1′-hexyloxy)ethyl-3-devinylpyropheophorobide-a], the meso pyropheophorbide-a [3-ethyl-3-devinyl-pyropheophorbide-a], and the corresponding 20-benzoic acid analogs were use...

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Detalhes bibliográficos
Main Authors: Mykhaylo Dukh, Joseph Cacaccio, Farukh A. Durrani, Ishaan Kumar, Ramona Watson, Walter A. Tabaczynski, Penny Joshi, Joseph R. Missert, Heinz Baumann, Ravindra K. Pandey
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-08-01
Colecção:European Journal of Medicinal Chemistry Reports
Assuntos:
Photodynamic therapy
Photosensitizer
Cancer imaging
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S277241742200019X
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