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Structural and dynamic insights into the role of conformational switching in the nuclease activity of the Xanthomonas albilineans Cas2 in CRISPR-mediated adaptive immunity

Clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins constitute a microbial, adaptive immune system countering invading nucleic acids. Cas2 is a universal Cas protein found in all types of CRISPR-Cas systems, and its role is implicated in new space...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Donghyun Ka, Suji Hong, Ugeene Jeong, Migyeong Jeong, Nayoung Suh, Jeong-Yong Suh, Euiyoung Bae
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: AIP Publishing LLC and ACA 2017-09-01
Sarja:Structural Dynamics
Linkit:http://dx.doi.org/10.1063/1.4984052
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