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Glycan masking of hemagglutinin for adenovirus vector and recombinant protein immunizations elicits broadly neutralizing antibodies against H5N1 avian influenza viruses.
The highly pathogenic avian influenza (HPAI) H5N1 virus, a known trigger of diseases in poultry and humans, is perceived as a serious threat to public health. There is a clear need for a broadly protective H5N1 vaccine or vaccines for inducing neutralizing antibodies against multiple clades/subclade...
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Main Authors: | , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
Public Library of Science (PLoS)
2014-01-01
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叢編: | PLoS ONE |
在線閱讀: | http://europepmc.org/articles/PMC3966833?pdf=render |
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