Glycan Masking of Hemagglutinin for Adenovirus Vector and Recombinant Protein Immunizations Elicits Broadly Neutralizing Antibodies against H5N1 Avian Influenza Viruses

The highly pathogenic avian influenza (HPAI) H5N1 virus, a known trigger of diseases in poultry and humans, is perceived as a serious threat to public health. There is a clear need for a broadly protective H5N1 vaccine or vaccines for inducing neutralizing antibodies against multiple clades/subclade...

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Main Authors: Lin, Shih-Chang, Liu, Wen-Chun, Jan, Jia-Tsrong, Wu, Suh-Chin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966833/
https://ncbi.nlm.nih.gov/pubmed/24671139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092822
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