Glycan masking of hemagglutinin for adenovirus vector and recombinant protein immunizations elicits broadly neutralizing antibodies against H5N1 avian influenza viruses.

The highly pathogenic avian influenza (HPAI) H5N1 virus, a known trigger of diseases in poultry and humans, is perceived as a serious threat to public health. There is a clear need for a broadly protective H5N1 vaccine or vaccines for inducing neutralizing antibodies against multiple clades/subclade...

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Huvudupphovsmän: Shih-Chang Lin, Wen-Chun Liu, Jia-Tsrong Jan, Suh-Chin Wu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC3966833?pdf=render
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