Epigenomic Profiling of Epithelial Ovarian Cancer Stem-Cell Differentiation Reveals GPD1 Associated Immune Suppressive Microenvironment and Poor Prognosis

Intraperitoneal metastasis is a challenging clinical scenario in epithelial ovarian cancer (EOC). As they are distinct from hematogenous metastasizing tumors, epithelial ovarian cancer cells primarily disseminate within the peritoneal cavity to form superficially invasive carcinomas. Unfavorable pha...

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Hauptverfasser: Lin-Yu Chen, Rui-Lan Huang, Po-Hsuan Su, Ling-Hui Chu, Yu-Chun Weng, Hui-Chen Wang, Hung-Cheng Lai, Kuo-Chang Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-05-01
Schriftenreihe:International Journal of Molecular Sciences
Schlagworte:
epigenetics
cancer stem cells
epithelial ovarian cancer
prognostic biomarker
Online Zugang:https://www.mdpi.com/1422-0067/23/9/5120
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