Structure and Dynamics of Mono- vs. Doubly Lipidated Rab5 in Membranes

The Rab5 small GTPase is a regulator of endosomal trafficking and vesicle fusion. It possesses two adjacent cysteine residues for post-translational geranylgeranylation at its C-terminus for the protein to associate with the early endosome membrane. We compare the effect of mono-lipidification of on...

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Detaylı Bibliyografya
Asıl Yazarlar: Eileen Münzberg, Matthias Stein
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2019-09-01
Seri Bilgileri:International Journal of Molecular Sciences
Konular:
gtpase
post-translation modification
molecular dynamics
lipid bilayer
diffusion
Online Erişim:https://www.mdpi.com/1422-0067/20/19/4773
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