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Protozoan ALKBH8 oxygenases display both DNA repair and tRNA modification activities.
The ALKBH family of Fe(II) and 2-oxoglutarate dependent oxygenases comprises enzymes that display sequence homology to AlkB from E. coli, a DNA repair enzyme that uses an oxidative mechanism to dealkylate methyl and etheno adducts on the nucleobases. Humans have nine different ALKBH proteins, ALKBH1...
में बचाया:
मुख्य लेखकों: | , , , , , , , , , , |
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स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
Public Library of Science (PLoS)
2014-01-01
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श्रृंखला: | PLoS ONE |
ऑनलाइन पहुंच: | http://europepmc.org/articles/PMC4051686?pdf=render |
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