Population pharmacokinetic analysis of tramadol and O-desmethyltramadol with genetic polymorphism of CYP2D6

Joomi Lee,1,* Hee-Doo Yoo,2,* Jung-Woo Bae,3 Sooyeun Lee,3 Kwang-Hee Shin11College of Pharmacy, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Republic of Korea; 2Department of Biostatistics and Bioinformatics, Pharma Partnering Inc., Seoul 06605, Republic of Ko...

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Main Authors: Lee J, Yoo H, Bae JW, Lee S, Shin K
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019-05-01
Colecção:Drug Design, Development and Therapy
Assuntos:
tramadol
O-desmethyltramadol
pharmacokinetics
population model
CYP2D6*10
Acesso em linha:https://www.dovepress.com/population-pharmacokinetic-analysis-of-tramadol-and-o-desmethyltramado-peer-reviewed-article-DDDT
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