Suppression of Ocular Vascular Inflammation through Peptide-Mediated Activation of Angiopoietin-Tie2 Signaling

Persistent inflammation is a complication associated with many ocular diseases. Changes in ocular vessels can amplify disease responses and contribute to vision loss by influencing the delivery of leukocytes to the eye, vascular leakage, and perfusion. Here, we report the anti-inflammatory activity...

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Bibliographic Details
Main Authors: Adam C. Mirando, Raquel Lima e Silva, Zenny Chu, Peter A. Campochiaro, Niranjan B. Pandey, Aleksander S. Popel
Format: Artigo
Language:Inglês
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
AXT107
peptide therapeutic
ocular diseases
endothelial activation
vascular permeability
vascular leakage
Online Access:https://www.mdpi.com/1422-0067/21/14/5142
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