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Genome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificity.

Many human pathogens produce phenotypic variants as a means to circumvent the host immune system and enhance survival and, as a potential consequence, exhibit increased virulence. For example, it has been known for almost 90 y that clinical isolates of the human bacterial pathogen group A streptococ...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2006-01-01
Colecção:PLoS Pathogens
Acesso em linha:http://dx.doi.org/10.1371/journal.ppat.0020005
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