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Genome-wide analysis of chemically induced mutations in mouse in phenotype-driven screens
BACKGROUND: N-ethyl-N-nitrosourea (ENU) mutagen has become the method of choice for inducing random mutations for forward genetics applications. However, distinguishing induced mutations from sequencing errors or sporadic mutations is difficult, which has hampered surveys of potential biases in the...
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| Publicado no: | BMC Genomics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623266/ https://ncbi.nlm.nih.gov/pubmed/26503232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2073-4 |
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