Airway microbial diversity is decreased in young children with cystic fibrosis compared to healthy controls but improved with CFTR modulation

Background: Culture-independent next generation sequencing has identified diverse microbial communities within the cystic fibrosis (CF) airway. The study objective was to test for differences in the upper airway microbiome of children with CF and healthy controls and age-related differences in child...

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Autori principali: Andrea Hahn, Aszia Burrell, Emily Ansusinha, Diane Peng, Hollis Chaney, Iman Sami, Geovanny F. Perez, Anastassios C. Koumbourlis, Robert McCarter, Robert J. Freishtat, Keith A. Crandall, Edith T. Zemanick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020-06-01
Serie:Heliyon
Soggetti:
Health sciences
Respiratory system
Infectious disease
Microbiology
Epidemiology
Pediatrics
Accesso online:http://www.sciencedirect.com/science/article/pii/S2405844020309488
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