MOLECULAR DESIGN OF N-ACYL DERIVATIVES OF 2-(2-OXOPYROLIDIN-1-YL)-ACETAMIDE WITH GABA-ERGIC AND GLUTAMATERGIC ACTIVITIES

The first of the most successfully implemented nootropic drugs in medical practice is piracetam, which should be attributed to cyclic derivatives of gamma-aminobutyric acid. The production of new piracetam derivatives with high nootropic activity is a promising direction in the development of new ne...

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Main Authors: I. P. Kodonidi, A. S. Chiriapkin, D. E. Tworowski
Format: Artigo
Jezik:Russo
Izdano: Pyatigorsk Medical and Pharmaceutical Institute - branch of Volgograd State Medical University 2021-06-01
Serija:Farmaciâ i Farmakologiâ (Pâtigorsk)
Teme:
2-(2-oxopyrolidin-1-yl)-acetamide
n-acyl derivatives
gabaa receptor
ampa receptor
nootropics
molecular design
molecular docking
structural pharmacology
qsar
Online dostop:https://www.pharmpharm.ru/jour/article/view/799
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