Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment

The identification of novel pan-sigma receptor (SR) modulators, potentially useful in cancer treatment, represents a new goal of our research. Here, we report on the preparation of novel chiral compounds characterized by a 3-C alkyl chain bridging an aromatic portion to a 4-benzyl-piperidine moiety....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Marta Rui, Annamaria Marra, Vittorio Pace, Markus Juza, Daniela Rossi, Simona Collina
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2016-09-01
श्रृंखला:Molecules
विषय:
sigma receptor (SR) modulators
amylose- and cellulose-derived CSPs
chiral resolution
enantioselective HPLC
electronic circular dichroism (ECD)
ऑनलाइन पहुंच:http://www.mdpi.com/1420-3049/21/9/1210
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