SNP association mapping across the extended major histocompatibility complex and risk of B-cell precursor acute lymphoblastic leukemia in children.

The extended major histocompatibility complex (xMHC) is the most gene-dense region of the genome and harbors a disproportionately large number of genes involved in immune function. The postulated role of infection in the causation of childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL)...

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Main Authors: Kevin Y Urayama, Anand P Chokkalingam, Catherine Metayer, Helen Hansen, Suzanne May, Patricia Ramsay, Joseph L Wiemels, John K Wiencke, Elizabeth Trachtenberg, Pamela Thompson, Yasushi Ishida, Paul Brennan, Kent W Jolly, Amanda M Termuhlen, Malcolm Taylor, Lisa F Barcellos, Patricia A Buffler
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3749982?pdf=render
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