HLA-DP genetic variation, proxies for early life immune modulation and childhood acute lymphoblastic leukemia risk

The human leukocyte antigen (HLA) genes are candidate genetic susceptibility loci for childhood acute lymphoblastic leukemia (ALL). We examined the effect of HLA-DP genetic variation on risk and evaluated its potential interaction with 4 proxies for early immune modulation, including measures of inf...

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Autori principali: Urayama, Kevin Y., Chokkalingam, Anand P., Metayer, Catherine, Ma, Xiaomei, Selvin, Steve, Barcellos, Lisa F., Wiemels, Joseph L., Wiencke, John K., Taylor, Malcolm, Brennan, Paul, Dahl, Gary V., Moonsamy, Priscilla, Erlich, Henry A., Trachtenberg, Elizabeth, Buffler, Patricia A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2012
Soggetti:
Lymphoid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471514/
https://ncbi.nlm.nih.gov/pubmed/22923493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-01-404723
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