Characterization of Endoplasmic Reticulum (ER) in Human Pluripotent Stem Cells Revealed Increased Susceptibility to Cell Death upon ER Stress

Human pluripotent stem cells (hPSCs), such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), have a well-orchestrated program for differentiation and self-renewal. However, the structural features of unique proteostatic-maintaining mechanisms in hPSCs and their features, dis...

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Main Authors: Tae Won Ha, Ji Hun Jeong, HyeonSeok Shin, Hyun Kyu Kim, Jeong Suk Im, Byung Hoo Song, Jacob Hanna, Jae Sang Oh, Dong-Hun Woo, Jaeseok Han, Man Ryul Lee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-04-01
Colecção:Cells
Assuntos:
human pluripotent stem cells
endoplasmic reticulum (ER)
ER stress
binding immunoglobulin protein (BiP)
C/EBP homologous protein (CHOP)
proteostasis
Acesso em linha:https://www.mdpi.com/2073-4409/9/5/1078
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