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Signaling in fibrosis: TGF-β, WNT, and YAP/TAZ converge
Chronic organ injury leads to fibrosis and eventually organ failure. Fibrosis is characterized by excessive synthesis, remodeling and contraction of extracellular matrix produced by myofibroblasts. Myofibroblasts are the key cells in the pathophysiology of fibrotic disorders and their differentiatio...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2015-09-01
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| Серии: | Frontiers in Medicine |
| Предметы: | |
| Online-ссылка: | http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00059/full |
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