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Signaling in fibrosis: TGF-β, WNT, and YAP/TAZ converge

Chronic organ injury leads to fibrosis and eventually organ failure. Fibrosis is characterized by excessive synthesis, remodeling and contraction of extracellular matrix produced by myofibroblasts. Myofibroblasts are the key cells in the pathophysiology of fibrotic disorders and their differentiatio...

詳細記述

保存先:
書誌詳細
主要な著者: Bram ePiersma, Ruud A Bank, Miriam eBoersema
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2015-09-01
シリーズ:Frontiers in Medicine
主題:
Wnt
オンライン・アクセス:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00059/full
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