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Signaling in fibrosis: TGF-β, WNT, and YAP/TAZ converge
Chronic organ injury leads to fibrosis and eventually organ failure. Fibrosis is characterized by excessive synthesis, remodeling and contraction of extracellular matrix produced by myofibroblasts. Myofibroblasts are the key cells in the pathophysiology of fibrotic disorders and their differentiatio...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Frontiers Media S.A.
2015-09-01
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シリーズ: | Frontiers in Medicine |
主題: | |
オンライン・アクセス: | http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00059/full |
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