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Signaling in fibrosis: TGF-β, WNT, and YAP/TAZ converge

Chronic organ injury leads to fibrosis and eventually organ failure. Fibrosis is characterized by excessive synthesis, remodeling and contraction of extracellular matrix produced by myofibroblasts. Myofibroblasts are the key cells in the pathophysiology of fibrotic disorders and their differentiatio...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bram ePiersma, Ruud A Bank, Miriam eBoersema
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2015-09-01
Sarja:Frontiers in Medicine
Aiheet:
Wnt
Linkit:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00059/full
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