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Signaling in fibrosis: TGF-β, WNT, and YAP/TAZ converge

Chronic organ injury leads to fibrosis and eventually organ failure. Fibrosis is characterized by excessive synthesis, remodeling and contraction of extracellular matrix produced by myofibroblasts. Myofibroblasts are the key cells in the pathophysiology of fibrotic disorders and their differentiatio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bram ePiersma, Ruud A Bank, Miriam eBoersema
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015-09-01
Cyfres:Frontiers in Medicine
Pynciau:
Wnt
Mynediad Ar-lein:http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00059/full
Tagiau: Ychwanegu Tag
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