Role of the TMPRSS2-ERG Gene Fusion in Prostate Cancer

TMPRSS2-ERG gene fusions are the predominant molecular subtype of prostate cancer. Here, we explored the role of TMPRSS2-ERG gene fusion product using in vitro and in vivo model systems. Transgenic mice expressing the ERG gene fusion product under androgen-regulation develop mouse prostatic intraepi...

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Main Authors: Scott A. Tomlins, Bharathi Laxman, Sooryanarayana Varambally, Xuhong Cao, Jindan Yu, Beth E. Helgeson, Qi Cao, John R. Prensner, Mark A. Rubin, Rajal B. Shah, Rohit Mehra, Arul M. Chinnaiyan
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2008-02-01
Series:Neoplasia: An International Journal for Oncology Research
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S1476558608800644
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