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In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide

A series of N1,N3-bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4–16 were prepared and their structures were confirmed by different spectral tools. The cytotoxic potentiality of novel compounds 4–16 was assessed by the MTT assay method on colon, lung and breast tumour cell lines. Compound...

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書誌詳細
主要な著者: Asmaa F. Kassem, Gaber O. Moustafa, Eman S. Nossier, Hemat S. Khalaf, Marwa M. Mounier, Suliman A. Al-Yousef, Sabry Y. Mahmoud
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis Group 2019-01-01
シリーズ:Journal of Enzyme Inhibition and Medicinal Chemistry
主題:
オンライン・アクセス:http://dx.doi.org/10.1080/14756366.2019.1613390
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