Macrophage Depletion Attenuates Extracellular Matrix Deposition and Ductular Reaction in a Mouse Model of Chronic Cholangiopathies.

Chronic cholangiopathies, such as primary and secondary sclerosing cholangitis, are progressive disease entities, associated with periportal accumulation of inflammatory cells, encompassing monocytes and macrophages, peribiliary extracellular matrix (ECM) deposition and ductular reaction (DR). This...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jan Best, Stefaan Verhulst, Wing-Kin Syn, Kimberly Lagaisse, Noemi van Hul, Femke Heindryckx, Jan-Peter Sowa, Liesbeth Peeters, Hans Van Vlierberghe, Isabelle A Leclercq, Ali Canbay, Laurent Dollé, Leo A van Grunsven
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2016-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC5019458?pdf=render
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