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Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer’s Disease

Amyloid-β (Aβ) accumulation and tauopathy are considered the pathological hallmarks of Alzheimer’s disease (AD), but attenuation in choline signaling, including decreased nicotinic acetylcholine receptors (nAChRs), is evident in the early phase of AD. Currently, there are no drugs that can suppress...

詳細記述

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書誌詳細
主要な著者: Kazuyuki Takata, Hiroyuki Kimura, Daijiro Yanagisawa, Koki Harada, Kaneyasu Nishimura, Yoshihisa Kitamura, Shun Shimohama, Ikuo Tooyama
フォーマット: Artigo
言語:Inglês
出版事項: MDPI AG 2022-04-01
シリーズ:Molecules
主題:
オンライン・アクセス:https://www.mdpi.com/1420-3049/27/9/2780
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