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Structure-Based Mechanism for Early PLP-Mediated Steps of Rabbit Cytosolic Serine Hydroxymethyltransferase Reaction

Serine hydroxymethyltransferase catalyzes the reversible interconversion of L-serine and glycine with transfer of one-carbon groups to and from tetrahydrofolate. Active site residue Thr254 is known to be involved in the transaldimination reaction, a crucial step in the catalytic mechanism of all pyr...

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Bibliografiska uppgifter
Huvudupphovsmän: Martino L. Di Salvo, J. Neel Scarsdale, Galina Kazanina, Roberto Contestabile, Verne Schirch, H. Tonie Wright
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Limited 2013-01-01
Serie:BioMed Research International
Länkar:http://dx.doi.org/10.1155/2013/458571
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