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Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial.

RTS,S, a candidate vaccine for malaria, is a recombinant protein expressed in yeast containing part of the circumsporozoite protein (CSP) sequence of 3D7 strain of Plasmodium falciparum linked to the hepatitis B surface antigen in a hybrid protein. The RTS,S antigen is formulated with GSK Biological...

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Autori principali: John N Waitumbi, Samuel B Anyona, Carol W Hunja, Carolyne M Kifude, Mark E Polhemus, Douglas S Walsh, Chris F Ockenhouse, D Gray Heppner, Amanda Leach, Marc Lievens, W Ripley Ballou, Joe D Cohen, Colin J Sutherland
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2009-11-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC2773849?pdf=render
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