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Pressure Overload-Induced Cardiac Hypertrophy Response Requires Janus Kinase 2-Histone Deacetylase 2 Signaling

Pressure overload induces cardiac hypertrophy through activation of Janus kinase 2 (Jak2), however, the underlying mechanisms remain largely unknown. In the current study, we tested whether histone deacetylase 2 (HDAC2) was involved in the process. We found that angiotensin II (Ang-II)-induced re-e...

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Detalhes bibliográficos
Main Authors: Huang Ying, Mao-Chun Xu, Jing-Hua Tan, Jing-Hua Shen, Hao Wang, Dai-Fu Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2014-11-01
Colecção:International Journal of Molecular Sciences
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Acesso em linha:http://www.mdpi.com/1422-0067/15/11/20240
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