Gene-based sequencing identifies lipid-influencing variants with ethnicity-specific effects in African Americans.

Although a considerable proportion of serum lipids loci identified in European ancestry individuals (EA) replicate in African Americans (AA), interethnic differences in the distribution of serum lipids suggest that some genetic determinants differ by ethnicity. We conducted a comprehensive evaluatio...

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Detalhes bibliográficos
Main Authors: Amy R Bentley, Guanjie Chen, Daniel Shriner, Ayo P Doumatey, Jie Zhou, Hanxia Huang, James C Mullikin, Robert W Blakesley, Nancy F Hansen, Gerard G Bouffard, Praveen F Cherukuri, Baishali Maskeri, Alice C Young, Adebowale Adeyemo, Charles N Rotimi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2014-03-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC3945436?pdf=render
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