Kinesin family member 23, regulated by FOXM1, promotes triple negative breast cancer progression via activating Wnt/β-catenin pathway

Abstract Background Triple negative breast cancer (TNBC) is highly malignant and has a worse prognosis, compared with other subtypes of breast cancer due to the absence of therapeutic targets. KIF23 plays a crucial role in the tumorigenesis and cancer progression. However, the role of KIF23 in devel...

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Detalhes bibliográficos
Main Authors: Zhi Li, Hai-Yan Yang, Xiao-Lan Zhang, Xu Zhang, Yu-Zhou Huang, Xin-Yuan Dai, Liang Shi, Guo-Ren Zhou, Ji-Fu Wei, Qiang Ding
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
Colecção:Journal of Experimental & Clinical Cancer Research
Assuntos:
KIF23
Wnt/β-catenin pathway
FOXM1
WDR5
H3K4me3
Triple negative breast cancer
Acesso em linha:https://doi.org/10.1186/s13046-022-02373-7
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