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The human TUT1 nucleotidyl transferase as a global regulator of microRNA abundance.

Post-transcriptional modifications of miRNAs with 3' non-templated nucleotide additions (NTA) are a common phenomenon, and for a handful of miRNAs the additions have been demonstrated to modulate miRNA stability. However, it is unknown for the vast majority of miRNAs whether nucleotide addition...

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Autori principali: Emily C Knouf, Stacia K Wyman, Muneesh Tewari
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3715485?pdf=render
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