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The proprotein convertase encoded by amontillado (amon) is required in Drosophila corpora cardiaca endocrine cells producing the glucose regulatory hormone AKH.

Peptide hormones are potent signaling molecules that coordinate animal physiology, behavior, and development. A key step in activation of these peptide signals is their proteolytic processing from propeptide precursors by a family of proteases, the subtilisin-like proprotein convertases (PCs). Here,...

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Detalhes bibliográficos
Main Authors: Jeanne M Rhea, Christian Wegener, Michael Bender
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-05-01
Colecção:PLoS Genetics
Acesso em linha:http://europepmc.org/articles/PMC2877730?pdf=render
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