ZAK Inhibitor PLX4720 Promotes Extrusion of Transformed Cells via Cell Competition

Summary: Previous studies have revealed that, at the initial step of carcinogenesis, transformed cells are often eliminated from epithelia via cell competition with the surrounding normal cells. In this study, we performed cell competition-based high-throughput screening for chemical compounds using...

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Detalhes bibliográficos
Main Authors: Takeshi Maruyama, Ayana Sasaki, Sayuri Iijima, Shiyu Ayukawa, Nobuhito Goda, Keisuke Tazuru, Norikazu Hashimoto, Takashi Hayashi, Kei Kozawa, Nanami Sato, Susumu Ishikawa, Tomoko Morita, Yasuyuki Fujita
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-07-01
Colecção:iScience
Assuntos:
Chemistry
Biological Sciences
Cancer
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2589004220305149
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