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Target Points in Trastuzumab Resistance
Epidermal growth factor (EGF) family of receptors is involved in cell growth and differentiation. The human EGF2 (HER2) lacks natural ligands, and correlation between HER2 levels and carcinogenesis makes the receptor an ideal candidate for targeted therapy in breast cancer. Trastuzumab is a humanize...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Limited
2012-01-01
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| Colecção: | International Journal of Breast Cancer |
| Acesso em linha: | http://dx.doi.org/10.1155/2012/761917 |
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