Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism

Trastuzumab shows remarkable efficacy in treatment of ErbB2-positive breast cancers when used alone or in combination with other chemotherapeutics. However, acquired resistance develops in most treated patients, necessitating alternate treatment strategies. Increased aerobic glycolysis is a hallmark...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhao, Yuhua, Liu, Hao, Liu, Zixing, Ding, Yan, LeDoux, Susan P., Wilson, Glenn L., Voellmy, Richard, Lin, Yifeng, Lin, Wensheng, Nahta, Rita, Liu, Bolin, Fodstad, Oystein, Chen, Jieqing, Wu, Yun, Price, Janet E., Tan, Ming
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129363/
https://ncbi.nlm.nih.gov/pubmed/21498634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0127
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