MicroRNA-98 Inhibits Hepatic Stellate Cell Activation and Attenuates Liver Fibrosis by Regulating HLF Expression

Liver fibrosis is a major endpoint of patients with chronic liver diseases. The molecular mechanisms behind liver fibrosis remain largely unknown. Many studies have indicated the role of microRNA (miRNA) in hepatic tumorigenesis. But the role of miRNA in liver fibrosis is little known. Activated hep...

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Auteurs principaux: Qi Wang, Song Wei, Haoming Zhou, Lei Li, Shun Zhou, Chengyu Shi, Yong Shi, Jiannan Qiu, Ling Lu
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020-06-01
Collection:Frontiers in Cell and Developmental Biology
Sujets:
microRNA-98
hepatic stellate cell
liver fibrosis
HLF
HIF-1α
Accès en ligne:https://www.frontiersin.org/article/10.3389/fcell.2020.00513/full
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